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DeCS
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Descriptor English:
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Maturation-Promoting Factor
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Descriptor Spanish:
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Factor Promotor de Maduración
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Descriptor Portuguese:
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Fator Promotor de Maturação
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Synonyms English:
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Histone H1 Kinase, Growth Associated
Histone H1 Kinase, Growth-Associated
Histone H1 Kinase, M Phase Specific
Histone H1 Kinase, M-Phase-Specific
M Phase Promoting Factor
M Phase-Promoting Factor
Maturation Promoting Factor
Mitosis Promoting Factor
Mitosis-Promoting Factor
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Tree Number:
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D08.811.913.696.620.682.700.646.500.984
D12.644.360.250.580
D12.776.167.200.580
D12.776.476.250.580
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Definition English:
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Protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by CYCLINS; MPF directly phosphorylates some of the proteins involved in nuclear envelope breakdown, chromosome condensation, spindle assembly, and the degradation of cyclins. The catalytic subunit of MPF is PROTEIN P34CDC2. |
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See Related English:
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Cyclins
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History Note English:
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91; HISTONE H1 KINASE, M-PHASE-SPECIFIC was HISTONE H1 KINASE, M PHASE-SPECIFIC 1991-93
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Allowable Qualifiers English:
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Record Number:
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29039
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Unique Identifier:
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D016200
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Occurrence in VHL:
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Similar:
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DeCS
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